2,3,5,6-四氟对苯二甲腈的合成

摘要

Reacting 2,3,5,6-tetrachlorophthalonitrile with KF in DMSO-tolue at 120～30 ℃ for 5 h produced 2,3,5,6-tetrafluoroterephthalonitrile with a yield of 76.5 % and purity of 98.5 %.A simple method was used to obtain anhydrous KF and DMF-Toluene.The effect on yield of reaction temperature and time and of other conditions is discussed.%2,3,5,6-四氯对苯二甲腈与氟化钾在DMSO-甲苯混合溶剂中于120～130℃反应5 h,产物2,3,5,6-四氟对苯二甲腈的收率为76.5%,含量98.5%。用简便的溶剂与水共沸去水对KF和DMSO-甲苯进行无水处理,讨论了反应温度、时间等条件对反应收率的影响。