意大利牛舌草化学成分及药理作用研究进展

摘要

Anchusa italica Retz. belongs to the Boraginaceae, the aerial parts are the medicinal parts. It can produce wet and hot things in body, so it can be used in palpitation, insomnia, obnubilation, headache, slow response, constipation. Modern pharmacology has demonstrated that it includes anticancer, antioxidant, antiviral, central nervous system function, endocrine function and many other effects. Anchusa italic Retz. chemical constituents including steroids, essential oil, alkaloids, tannins, oil, triterpenes, flavonoids and polyphenols. By looking up the literatures of domestic and overseas, the present review will highlight the chemical compositions and pharmacological effects of Anchusa italica Retaz. . in order to give reference for its study and development.%意大利牛舌草为紫草科牛舌草属多年生草本植物的地上部分，具有生湿生热、调节异常黑胆质等功效，用于心悸、失眠、神志不安、头痛、反应迟钝、大便秘结。现代药理学研究表明其具有抗肿瘤、抗氧化、抗病毒、抗菌、中枢神经系统作用、内分泌作用等生物活性。意大利牛舌草化学成分包括甾体、挥发油、生物碱、鞣质、油脂、三萜、黄酮和多酚类化合物。本文通过查阅近期国内外相关文献，从化学成分和药理作用两方面对意大利牛舌草进行文献综述，以期为该属植物的进一步研究提供参考。