鸭坦布苏病毒试验感染麻鸭的组织病理学研究

摘要

以经肌肉注射途径人工感染鸭坦布苏病毒的110日龄麻鸭为试验材料,研究感染麻鸭的眼观及组织病理学变化.研究发现,感染麻鸭的眼观病变为卵泡充血、出血、变性.组织学病变为卵泡充血、出血,卵泡颗粒细胞坏死,卵巢内异嗜性白细胞浸润,卵黄液溶解;肝脏间质结缔组织及胆管增生;肝脏、胰腺、肾脏、腺胃中淋巴细胞浸润;肠道呈卡他性肠炎.以上结果表明,鸭坦布苏病毒感染麻鸭以卵巢病变为特征,表现为卵泡充血、出血、变性,卵巢内异嗜性白细胞浸润等症状.%The gross morphologic and histopathologic changes of 110 day-old female sheldrake ducks were analyzed after experimentally infected with Tembusu virus.The most prominent gross changes were hyperemia,hemorrhage and degeneration in ovarian follicle.Histopathologic changes were hyperemia,hemorrhage of ovarian follicle,necrosis of granulosa cells,and infiltration of heterophils in ovary and lysis of egg yolk.Other lesions were proliferation of connective tissue and bile duct in interstitium of live,infiltration of lymphocyte in the live,lung,kidney,pancreas and glandular stomach.The results showed that infection of Tembusu virus in sheldrake ducks is correlated highly with ovarian lesions,which showing hyperemia,hemorrhage and degeneration in ovarian follicle,and infiltration of heterophils in the ovary.This study of gross morphologic and histopathologic changes of infected ducks was helpful for clinical rapid diagnosis of the duck Tembusu virus disease.