首页> 中文期刊>食品研究与开发 >红心猕猴桃不同部位提取物抗肿瘤活性研究

红心猕猴桃不同部位提取物抗肿瘤活性研究

     

摘要

In order to investigate the inhibitory activities to three human cancer cell lines(gastric cancer MGC-803, cervical cancer Hela and hepatic carcinoma HepG2 cell lines) of the fractions from the different parts (root, branch, leave and fruit) of red-fleshed kiwifruit(Actinidia chinensis) from Guangxi, Leye country. The fractions of the different parts were obtained by extracting with EtOH-H 2O as solvent. The inhibitory activities in vitro on MGC-803 cell lines were evaluated by using MTT method, and Hela along with HepG2 cell lines were evaluated by using CCK-8 method. According to the bioassay in virto, The EtOAc fraction of branch, the E-tOH-H2O (90:10) along with H2O fractions of fruit had better inhibitory activities on MGC-803 cells, and the H2O fraction of branch, the EtOH-H2O (50:50) together with H2O fractions of fruit possessed better activities against Hela cells growing. Thus the red-fleshed kiwifruit had some activities against MGC-803 and Hela cells growing, and the activity of fruit was the best.%为评价乐业红心猕猴桃不同部位提取物体外抗胃癌MGC-803、 宫颈癌Hela和肝癌HepG23种细胞株的生物活性.使用酒精-水混合溶剂分别提取红心猕猴桃不同部位(根、枝、叶和果实)获得不同部位提取物;使用MTT法评价不同部位提取物体外抗胃癌活性,使用CCK-8法评价不同部分体外抗宫颈癌和肝癌活性.结果表明在抗胃癌MGC-803活性中,枝的乙酯组分、果实的90%酒精组分和果实组分的活性较好,而在抗宫颈癌Hela活性中,枝的水组分、果实50%酒精组分和果实水组分活性比较好.因此乐业红心猕猴桃具有一定抑制胃癌MGC-803和宫颈癌Hela细胞生长活性,其中果实部位活性最好.

著录项

  • 来源
    《食品研究与开发》|2017年第6期|178-181|共4页
  • 作者单位

    右江民族医学院药学院,广西百色533000;

    广西高校右江流域特色民族药研究重点实验室,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    广西高校右江流域特色民族药研究重点实验室,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    右江民族医学院药学院,广西百色533000;

    右江民族医学院药学院,广西百色533000;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类
  • 关键词

    抗肿瘤; 不同部位; 提取物; 红心猕猴桃;

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