2012-2014年武警江苏省总队医院抗肿瘤药应用分析

摘要

目的：了解武警江苏省总队医院（以下简称“我院”）抗肿瘤药的临床应用情况及发展趋势，为临床合理用药提供参考。方法：采用销售金额排序法、用药频率（ defined daily dose system，DDDs）排序法和限定日费用（ daily drug cost，DDC）排序法对我院2012—2014年抗肿瘤药用药数据进行统计、分析。结果：我院2012—2014年抗肿瘤药销售总金额和使用总频率呈逐年增长趋势，单个药物3年中DDC波动幅度较小，总体趋于稳定。其中，多西他赛、奥沙利铂、吉西他滨和帕米膦酸3年中销售金额一直位于前5名内，使用频率较高的药物为氟尿嘧啶和顺铂，交替出现在DDDs排序前2位。结论：我院抗肿瘤药应用情况基本合理，但仍需对抗肿瘤药物的应用管理，进一步加强临床用药的合理应用。%OBJECTIVE:To investigate the status quo and development tendency of anti-tumor drugs in the Armed Police Corps Hospital of Jiangsu Province ( hereinafter referred to as our hospital ) , and to provide reference for the rational drug use in clinic.METHODS:The medication data of anti-tumor drugs in our hospital during 2012-2014 were statistically analyzed by using consumption sum ranking method, defined daily dose system( DDDs) ranking method and defined daily cost ( DDC) ranking method.RESULTS: The consumption sum and DDDs of anti-tumor drugs had an increasing trend year by year in our hospital during 2012-2014 .The DDC of single drug had a small volatility but it was stable in general.Docetaxel, oxaliplatin, gemcitabine and pamidronate dominated the top 5 places ranked by consumption sum during the three years, meanwhile, fluorouracil and cisplatin both had high application frequency, which were listed on the top 2 in turn ranked by DDDs.CONCLUSIONS: The current status of anti-tumor drugs is basically rationally in our hospital, but the monitoring on clinical application of anti-tumor drugs still needs to be intensified, so as to further strengthen the rational drug use in clinic.