2011-2013年我院住院患者抗菌药物使用强度分析

摘要

目的：了解天津市东丽区东丽医院（以下简称“我院”）住院患者抗菌药物使用强度（ antibiotics use density，AUD）及趋势，提高合理用药水平。方法：从我院抗菌药物计算机管理软件系统中查询2011—2013年抗菌药物应用情况，计算AUD并进行分析。结果：我院AUD呈下降趋势，AUD排序居前5位的抗菌药物种类为第2代头孢菌素、青霉素类、氟喹诺酮类、其他β－内酰胺类、第3代头孢菌素。 AUD排序均居前10位的抗菌药物为美洛西林、头孢呋辛、头孢替安、头孢米诺和氨曲南等。结论：我院抗菌药物可能存在用药集中、用药过度、药物滥用、级别偏高等问题，应进一步细化管理措施，建立完善、长效机制，促进合理用药。%OBJECTIVE:To analyze the antibiotic use density ( AUD) and tendency of the antibiotic use in Tianjin Dongli District Dongli Hospital ( hereinafter referred to as the“our hospital”) in order to improve the level of rational use of drug.METHODS:The antibiotic use data from 2011 to 2013 were retrieved from computer management software system in our hospital, with AUD computed and analyzed.RESULTS: The AUD in our hospital showed a downward trend.The top five categories in terms of AUD were the second generation cephalosporins, penicillins, quinolones, other beta-lactams, and the third generation cephalosporins. Mezlocillin, cefuroxime, cefazolin, cefotiam and aztreonam were ranked among the top 10 antibiotics in terms of AUD.The AUD in all the departments except the departments of urology and general surgery showed downward trend.CONCLUSIONS:The antibiotic use in our hospital presents with the problem of centralized and excessive medication, abuse, high level of drugs etc.It is important to further refine management measures and establish improved long-term mechanism to promote rational use of drugs.