静脉药物配置中心常见医嘱不合理用药分析

摘要

OBJECTIVE:To investigate the intervention on irrational medical orders by prescription audit pharmacists in the Pharmacy Intravenous Admixture Service ( PIVAS ) of the First Affiliated Hospital of Kunming Medical University ( hereinafter referred to as “our hospital”) , so as to provide reference for the rational application of drugs in clinic .METHODS:Analysis was conducted on the irrational medical orders intervened by prescription audit pharmacists in PIVAS and the improvement suggestions provided by clinicians from Apr .2015 to Mar.2016. RESULTS:Totally 3 645 cases of irrational medical orders for pharmacists intervention were analyzed , and 3 275 cases were changed by clinicians with the rate of 89.85%.The irrational types of drug application were respectively overdose administration , improper concentration , improper dosing frequency , improper solvent , input error , irrational drug selection , improper compatibility , over course of treatment , repeated administration , improper route of administration , over indications of drug application and other irrational medications .CONCLUSIONS: The application rationality of drug application can be guaranteed greatly through the intervention of on total medical orders review by prescription audit pharmacists , which promote the rational application of drugs in clinic and benign development of PIVAS .%目的：了解昆明医科大学第一附属医院（以下简称“我院”）静脉药物配置中心（ pharmacy intravenous admixture service ， PIVAS）审方药师干预不合理医嘱情况，为临床合理用药提供依据。方法：对我院2015年4月—2016年3月PIVAS审方药师干预的医嘱不合理用药及临床医师更改情况进行分析。结果：共分析审方药师干预的3645例医嘱不合理用药，临床医师更改3275例，更改率为89．85％；不合理用药类型涉及超量、浓度不当、给药频次不当、溶剂不当、录入错误、药物遴选不合理、配伍不当、超疗程用药、重复用药、给药途径不当、超适应证用药以及其他等方面。结论：通过审方药师的全医嘱干预，极大程度的保证了临床用药的合理性，促进了临床合理用药及PIVAS用药的良性发展。