OBJECTIVE:To observe the clinical efficacy of nasal continuous positive airway pressure( NCPAP) in adjuvant treatment of infants with congenital heart disease complicated by pneumonia.METHODS:100 cases of left-right shunt children with congenital heart disease complicated by pneumonia were randomly selected to be divided into control group and observation group via the random number table, with 50 cases in each.The observation group were treated with routine treatment combined with NCPAP, while the control group only received routine treatment.The changes of vital signs as heart rate, respiratory rate and blood acid-alkali indexes in two groups were observed before and after treatment of 12 h, 24 h and 48 h, the clinical efficacy were compared between two groups.RESULTS:After treatment of 12 h, the heart rate and respiratory rate in observation group decreased significantly, yet still better than that of control group ( P<0.05 ) .And the blood acid-alkali indexes of observation group had been improved more significantly than that of control group(P<0.05), the trend continued over curative time.The remission rate and intubation rate of observation group were 90.0%( 45/50 ) and 2.0%( 1/50 ) , while the control group were 62.0%(31/50) and 8.0%(4/50),with statistically significant difference(P<0.05).CONCLUSIONS:NCPAP therapy can significantly improve the cardiorespiratory function of left-right shunt children with congenital heart disease complicated by pneumonia, relief the symptoms, reduce intubation rate and shorten length of stay.%目的：观察经鼻持续气道正压通气（ nasal continuous positive airway pressure，NCPAP）对先天性心脏病合并肺炎患儿的临床疗效。方法：选取左向右分流型先天性心脏病合并肺炎患儿100例，以随机数字表法分为观察组和对照组各50例。观察组患儿给予常规基础治疗并辅以NCPAP治疗，对照组患儿仅给予常规基础治疗。在开始治疗时及治疗12、24、48 h记录患儿的心率、呼吸频率等生命体征以及血气指标的变化，比较2组患儿的临床疗效。结果：治疗12 h，观察组患儿的心率和呼吸频率明显下降，优于对照组，血气分析指标较对照组明显改善，差异均有统计学意义（P＜0.05），此改变趋势随着治疗时间的推移而持续；观察组患儿的症状缓解率为90.0％（45／50）、插管率为2.0％（1／50），对照组分别为62.0％（31／50）、8.0％（4／50），2组的差异均有统计学意义（ P＜0.05）。结论：NCPAP治疗能显著改善左向右分流型先天性心脏病合并肺炎患儿的心肺功能，缓解患儿症状，降低插管率，缩短住院时间。
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