OBJECTIVE:To investigate the effects of folic acid supplementation in women of childbearing age before and after pregnancy on improving pregnancy outcome and reducing pregnancy complications .METHODS:595 women in preparation for pregnancy admitted from Sept .2009 to Mar.2014 were selected to be divided into observation group and control group via the random number table .300 cases in observation group were treated with folic acid , while the control group did not .The occurrence of pregnancy outcomes and complications were compared between two groups .RESULTS:The incidence of premature and low birth weight infants , induced abortion and stillbirth of observation group were significantly lower than that of control group , with statistically significant difference ( P<0.05 ) .The incidence of cleft lip and palate , neural tube defects , hypertensive disease pregnancy and fetal distress of observation group were significantly lower than that of control group , with statistically significant difference (P<0.05).CONCLUSIONS:Folic acid supplementation is necessary for women of childbearing age , which can not only improve the pregnancy outcomes , but also educe the incidence of pregnancy complications .It is worthy of clinical application and promotion .%目的：探讨育龄妇女在妊娠前后增补叶酸对改善妊娠结局、减少妊娠并发症的影响。方法：选择2009年9月—2014年3月595例准备妊娠的妇女作为研究对象，按照随机数字表法分为观察组和对照组。观察组300例妊娠期妇女服用叶酸，对照组295例未服用叶酸，比较2组妊娠期妇女的妊娠结局及妊娠并发症发生情况。结果：观察组早产儿、足月低体质量儿、引产儿及死胎发生率均明显低于对照组，差异均有统计学意义（P＜0.05）；观察组新生儿唇腭裂、新生儿神经管畸形、妊娠高血压病和胎儿窘迫的发生率均明显低于对照组，差异均有统计学意义（ P＜0.05）。结论：育龄妇女增补叶酸十分必要，不仅可以改善妊娠结局，还可降低妊娠并发症的发生率，值得临床推广。
展开▼
