OBJECTIVE:To investigate the effects of Radix scutellariae aluminum capsules in prevention of postoperative infection of appendicitis .METHODS:186 patients with acute appendicitis admitted from Jan .2012 to Dec. 2015 were selected to be divided into control group and observation group via the random number table , with 93 cases in each.The control group were treated with routine antibiotics after appendicitis surgery , while observation group additionally received Radix scutellariae aluminum capsules based on the control group .The wound infection , expression level of inflammatory factors , wound healing , body temperature after surgery , exhausting , length of stay and adverse drug reactions were compared between two groups .RESULTS:The infection rate of observation group after surgery was 3.23%(3/93), significantly lower than that of control group 11.83%(3/93), with statistically significant difference (P <0.05) .The CD4+of observation group were higher than that of control group , while CD4 +/CD8+, interleukin 6,interleukin 10, tumor necrosis factor αwere lower than that of control group , with statistically significant difference ( P<0.05) .The class A healing rate of observation group was 74.19%( 69/93 ) , significantly higher than that of control group 63.44%(59/93);the class C healing rate of observation group was 2.15%(2/93) , significantly lower than that of control group 10.75%(10/93), with statistically significant difference (P<0.05).The postoperative recovery time of body temperature , exhausting and length of stay of observation group were significantly lower than that of control group , with statistically significant difference ( P<0.05) .There were no adverse drug reactions in two groups during treatment . CONCLUSIONS: The effects of Radix scutellariae aluminum capsules in prevention of postoperative infection of appendicitis is remarkable , which can reduce the postoperative infection rate , improve symptoms in patients , shorten the length of stay with high safety .It is worthy of clinical application and promotion .%目的：探讨黄芩素铝胶囊预防阑尾炎术后感染的效果。方法：选择2012年1月—2015年12月收治的急性阑尾炎186例，按随机数字表法分为对照组和观察组各93例。对照组患者在阑尾炎术后给予常规抗菌药物，观察组在对照组治疗的基础上给予黄芩素铝胶囊。比较2组患者的切口感染情况，炎性因子表达水平，切口愈合情况，术后体温、排气和住院时间及不良反应发生情况。结果：观察组患者术后感染率为3．23％（3／93），明显低于对照组的11．83％（3／93），差异有统计学意义（P＜0．05）。观察组患者CD4＋水平高于对照组，而CD4＋／CD8＋、白细胞介素6、白细胞介素10、肿瘤坏死因子α水平均低于对照组，差异有统计学意义（P＜0．05）。观察组患者甲级愈合率为74．19％（69／93），明显高于对照组的63．44％（59／93）；观察组患者丙级愈合率为2．15％（2／93），明显低于对照组的10．75％（10／93），差异均有统计学意义（P＜0．05）。观察组患者术后体温恢复、排气和住院时间均明显短于对照组，差异有统计学意义（P＜0．05）。2组患者均未见明显不良反应。结论：黄芩素铝胶囊防阑尾炎术后感染效果较好，可降低术后感染率，改善患者症状，缩短住院时间，且安全性较高，值得临床推广。
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