OBJECTIVE:To improve the work of special comments on antibiotics prescriptions in Suzhou Municipal Hospital ( hereinafter referred to as “our hospital”) , and to promote the rational drug use in clinic .METHODS:Continuous quality improvement was conduced to find out the problems in antibiotics prescriptions .Combined with the actual situation of our hospital , the related scheme was formulated to solve these problems , and then the further implement and adjustment were adopted .Special comments were conducted on 174 255 outpatient and emergency antibiotics prescriptions which were extracted from Jul .2011 to Dec.2012.RESULTS: After the continuous quality improvement , the ratio of consumption sum of outpatient and emergency antibiotics versus the total consumption sum decreased from 29.42%(12 089 092.29 yuan/41 098 082.31 yuan) in 2011 to 20.47%(11 203 148.72 yuan/54 740 644.66 yuan);and the defined daily dose system decreased from 847 075.23 in 2011 to 562 325.01 in 2014.The highest rate of irrational outpatient and emergency antibiotics prescriptions was 10.53%( 503 prescriptions/4 775 prescriptions ) in Dec .2011 , which was in a decrease trend year by year , and maintained a low level within 1% in each month of 2014. CONCLUSIONS: Our hospital has formed the complete routine of continuous quality improvement , which increase the rational level of application of antibiotics , yet decrease the application amount of antibiotics .It still needs the further improvement .%目的：完善苏州市立医院（以下简称“我院”）抗菌药物处方专项点评工作，促进临床合理用药。方法：实施持续质量改进措施，在处方点评工作中不断发现问题，结合医院实际情况，制定解决问题的方案，并进一步实施及调整。抽取2011年7月—2014年12月门、急诊抗菌药物处方共174255张，对其进行专项点评。结果：实施持续质量改进措施后，我院门、急诊抗菌药物销售金额占药品总销售金额的比例由2011年的29．42％（12089092．29元／41098082．31元）逐步降至2014年的20．47％（11203148．72元／54740644．66元）；用药频度由2011年的847075．23逐步降至2014年的562325．01；门、急诊抗菌药物处方不合理率最高的为2011年12月的10．53％（503张／4775张），后逐年降低，2014年各月处方不合理率均保持在1％以内。结论：我院已形成一套自己的持续质量改进工作程序，提高了我院抗菌药物合理应用水平，减少了抗菌药物的使用，但还需进一步完善。
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