1920份住院患者注射用质子泵抑制剂病历用药调查与合理性分析

摘要

目的:探讨邵阳市第一人民医院(以下简称"该院")住院患者注射用质子泵抑制剂(proton pump inhibitor,PPI)使用情况及其合理性,为促进该类药物的合理应用提供参考.方法:制订注射用PPI临床应用合理性评价标准,从医院信息系统中抽取2016年4-5月该院使用注射用PPI的住院患者病历1 920份,按照评价标准,对注射用PPI的适应证、用药品种、给药途径、用法与用量、疗程等方面进行评价及分析.结果:1 920份使用注射用PPI的病历中,不合理用药715份,不合理用药率为37.2%;存在的主要问题为无指征预防性用药、给药途径不适宜及疗程过长等.结论:该院住院患者注射用PPI的使用存在不合理现象,医院应运用质量管理工具进行持续整改,促进注射用PPI的合理应用.%OBJECTIVE:To probe into the application and its rationality of proton pump inhibitor(PPI)for injection in 1 920 medical records of inpatients in the First People`s Hospital of Shaoyang (hereinafter referred to as "this hospital"), so as to provide references for rational drug application. METHODS:To formulate an evaluation criterion of clinical rational application of PPI for injection, 1920 medical orders of inpatients in this hospital from Apr. 2016 to May. 2016 were extracted from hospital information system, the indications, species, administration route, usage and dosage and treatment course of PPI were evaluated and analyzed according to the evaluation criterion. RESULTS:Of 1 920 medical orders, there were 715 with irrational drug application, accounted for 37.2%; mainly included non-indication preventive drug application, inappropriate administration route, overlong treatment course, etc. CONCLUSIONS:There are irrational applications of PPI for injection in this hospital, quality control should be applied on rectifying and reforming, so as to promote rational application of PPI for injection.