滋肾育胎丸联合地屈孕酮片治疗早期先兆流产的疗效观察

摘要

OBJECTIVE:To probe into the clinical effects of Zishenyutai pills combined with Dydrogesterone tablets in treatment of early threatened abortion.METHODS: 150 patients with threatened abortion admitted into Shenzhen Bao'an District Traditional Chinese Medicine Hospital from Oct.2012 to Oct.2016 were selected to be divided into observation group and control group via the admission sequence, with 75 cases in each.The observation group was given Zishenyutai pills combined with Dydrogesterone tablets, while the control group received progesterone intramuscular injections.The efficacy and changes of whole high blood viscosity, HCT, FIB levels of two groups were compared between two groups before and after treatment.RESULTS: The total effective rate of observation group was 85.33%(64/75), and control group was 53.33%(50/75), the difference was statistically significant(P<0.05).After treatment, the FIB and whole high blood viscosity decreased significantly in both groups compared with before treatment, and the observation group was better than the control group, the difference was statistically significant(P<0.05).CONCLUSIONS: The effects of Zishenyutai pills combined with Dydrogesterone tablets in treatment of early threatened abortion is significant, which can significantly improve the hemodynamics of patients.%目的:探讨滋肾育胎丸联合地屈孕酮片治疗早期先兆流产的临床效果.方法:收集2012年10月-2016年10月深圳市宝安区中医院收治的早期先兆流产患者150例,按入院先后顺序随机分为观察组和对照组,每组75例.观察组患者给予滋肾育胎丸联合地屈孕酮片治疗,对照组患者给予黄体酮肌内注射.比较两组患者的疗效及治疗前后全血高切黏度、红细胞比容、血浆纤维蛋白原(FIB)水平变化情况.结果:观察组患者的总有效率为85.33%(64/75),对照组为53.33%(50/75),两组的差异有统计学意义(P<0.05);治疗后,两组患者FIB、全血高切黏度均较治疗前明显降低,且观察组下降程度明显优于对照组,差异有统计学意义(P<0.05).结论:滋肾育胎丸联合地屈孕酮片治疗早期先兆流产效果明显,可显著改善患者血液流变学指标.