右美托咪定及丙泊酚联合地佐辛用于宫腔镜手术麻醉的效果观察

摘要

OBJECTIVE:To probe into the anesthetic effects of dexmedetomidine and propofol combined with dezocine in treatment of hysteroscope operation .METHODS:100 patients with hysteroscope operation were selected to be divided into observation group and control group via the random number table , with 50 cases in each.The observation group were treated with dexmedetomidine and propofol combined with dezocine , while the control group only received propofol .The anesthetic effects , incidence of adverse drug reactions , pain at different time points and changes of vital signs indicators of two groups were observed .RESULTS: The onset time , recovery time of directive force, eye-opening time in observation group were better than those of control group , with statistically significant difference ( P<0.05 ) .The incidence of adverse drug reactions of observation group was 2.00%( 1/50 ) , significantly lower than that of control group [ 28.00%( 14/50 ) ] , with statistically significant difference ( P<0.05 ) .The pain score of observation group during operation , after operation of 2 h, 12 h and 24 h were significantly lower than those in control group , with statistically significant difference ( P<0.05 ) .The vital signs indicators of observation group were significantly better than those of control group , with statistically significant difference ( P<0.05 ) .CONCLUSIONS:The effects of dexmedetomidine and propofol combined with dezocine in treatment of hysteroscope operation is significant , which can ensure patients'comforts and improve the operation safety .%目的：探讨宫腔镜手术中应用右美托咪定、丙泊酚联合地佐辛麻醉的效果。方法：选取100例宫腔镜手术患者，按照随机数字表法分为观察组和对照组，每组各50例。观察组患者给予右美托咪定、丙泊酚联合地佐辛麻醉，对照组患者给予丙泊酚麻醉，观察2组患者的麻醉效果、不良反应发生情况、不同时间段疼痛情况及生命体征各指标变化情况。结果：观察组患者麻醉起效时间、定向力恢复时间、睁眼时间均明显优于对照组，丙泊酚用量明显少于对照组，差异均有统计学意义（ P＜0.05）；观察组患者不良反应发生率为2.00％（1／50），明显低于对照组的28.00％（14／50），差异有统计学意义（P＜0.05）；观察组患者术中，术后2、12、24 h疼痛评分均明显低于对照组，差异均有统计学意义（ P＜0.05）；观察组患者术中、术后各项生命体征指标明显优于对照组，差异有统计学意义（ P＜0.05）。结论：宫腔镜手术中应用右美托咪定、丙泊酚联合地佐辛麻醉，效果显著，可保证患者舒适度，提高手术安全性。