Cancer Science Institute of Singapore,National University of Singapore,Centre for Translational Medicine,Singapore 117599,Singapore;
Department of Medicine,Yong Loo Lin School of Medicine,National University of Singapore,Singapore 119074,Singapore;
Department of Hematology-Oncology,National University Cancer Institute,NUHS,Singapore 119228,Singapore;
Multiple; myeloma; Proteasome; inhibitor; Bortezomib; Proteasome; β5-subunit; Drug; resistance; Clonal; evolution; Combination; therapy;