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信迪利单抗致间质性肺炎1例的药学监护

         

摘要

免疫检查点抑制剂(ICIs)的应用开创了癌症治疗的新时代,给恶性肿瘤患者带来了显著临床获益,延长了患者生存。ICIs通过靶向程序性细胞死亡蛋白-1/程序性细胞死亡配体-1(PD-1/PD-L1)和细胞毒性T淋巴细胞相关抗原4增强T淋巴细胞对癌细胞的细胞毒性^([1])。

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