A male 10-year-old Maltese dog with bilateral cryptorchid was presented for a mass in the left inguinal region,which was swelling and first noted by the owners about 2 months before presentation. The dog had been treated at local clinic by medication. On physical examination,he weighed 2. 4 kg and showed depressed,cutaneous ecchymotic hemorrhages,swelling prepuce and hair loss on the abdomen. A large firm mass was palpated in the left inguinal region. His body temperature was 39. 1 ℃ and his heart rate was 120 beats/min. Castration was recommended. The hematological analysis indicated the dog was suffering from a moderate leucopenia and severe thrombocytopenia (WBC: 21. 0×103/μL,PLT: 5×103/ μL). High level of estradiol-17β was determinate (estradiol-17β: 72. 96 pg/mL). Based on the hematological and hormonal examinations,testicular neoplasia was suspected. Both testicles were surgical removal by castration and histopathologically examined. Grossly,the right testis (1. 0×1. 0×0. 8 cm) was atrophic while the left (4. 0×3. 0×2. 0 cm) was irregularly ovoid and the cut surface was yellowish white and quite firm. Histological examinations confirmed the diagnosis of a Sertoli cell tumor with a diffuse distribution pattern. Postoperative treatment included blood transfusions,fluids therapy,antibiotics and Vitamin K. However,the dog kept bloody diarrhea and the following CBC test indicating a moderate nonregenerative normocytic and slightly hypochromic anemia,leucopenia as well as thrombocytopenia (hematocrit: 24. 3%,hemoglobin: 7. 7 g/dL,RBC: 3. 26×106/ μL,WBC: 0. 7×103/ μL,PLT: 4×103/ μL). Two days post operation,the dog went into a coma and died. Therefore,hormonal determination and blood transfusion may be considered before castration or other operation performance in case the CBC was suspected.
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