目的探讨α2 b干扰素联合利巴韦林气雾剂治疗手足口病的疗效和安全性。方法将80例手足口病患者随机分为治疗组和对照组，每组各40例。治疗组采用肌注α2 b干扰素加利巴韦林气雾剂喷雾吸入治疗，对照组采用静脉滴注利巴韦林再联合蒙脱石散涂布口腔，然后对两组的治疗效果进行比较。结果治疗组的有效率是87.5%，对照组的有效率是62.5%，两组比较，差异有统计学意义（P<0.05）；治疗组在退热时间、口腔溃疡愈合时间及进食时间方面比对照组有明显的优势。结论α2b干扰素联合利巴韦林气雾剂治疗手足口病有显著的疗效，并且安全可靠，没有明显不良反应。%Objective To observe the efifcacy and safety ofα2 b interferon and ribavirin aerosol treatment of hand, foot and mouth disease. Methods 80 cases of hand, foot and mouth disease were randomly divided into two groups, 40 cases each. Treatment group were treated intramuscularlyα2 b interferon plus ribavirin aerosol spray inhalation therapy, the control group was treated with intravenous infusion of the bulk coating oral ribavirin joint montmorillonite, and then compare the therapeutic effect of the two groups . Results Through the analysis of the treatment group, 87.5%efifciency the control group efifciency is 62.5%, and then compare the two groups, signiifcant difference (P<0.05), there are signiifcant;treatment group retreat hot, oral ulcer healing time and can eat a signiifcant advantage compared with the control group. Conclusion α2 b interferon and ribavirin aerosol treatment of hand, foot and mouth disease has signiifcant efifcacy and safe and reliable, no signiifcant adverse reactions.
展开▼
