Objective To analyze the risk factors of casescombined hospital-acquired pneumonia with acute intracerebral hemorrhage in Intensive Care Unit. In order to provide the basis for prevention of nosocomial infection in ICU. Methods 189 cases from January 2010 to January 2011 in our hospital ICU, were divided into case group (57 cases) and control group (132 cases), according to whether HAP occur or not. Risk factors were analysed by multi-factor non-conditional Logistic regression analysis. Results The rate of rebleeding andthe mortality rate of the case group were higher than the control group, the difference was statisticaly significant (P<0.01). The BI score of the case group was significantly lower than the control group, the was statisticaly significant (P<0.01), Tracheotomy treatment, above 60 years of age (OR=3.674;95 CI:0.757~14.745), smoking (OR=76.775;95 CI:0.354~17.475), Tracheotomy in treatment of tracheal intubation treatment (OR=26.464;95 CI:0.676~18.864), ICU, hospitalization (OR=5.772;95 CI:0.428~6.642), the duration of mechanical ventilation (OR=3.425;95 CI:0.208~6.277) were the risk factors for pneumonia of thepatients with acute cerebral hemorrhage chamber in ICU. Conclusion The prognosis of the patients combined acute cerebral hemorrhage with HAPin ICU is poor. Invasive operation times should be reduced, extubation as early as possible, avoid long time in ICU admission and mechanical ventilation.% 目的调查研究急性脑出血患者ICU室罹患院内获得性肺炎 HAP 的危险因素,为预防ICU院内感染提供参考依据.方法2010年1月~2011年2月在广西钦州市灵山县人民医院ICU进行住院治疗的189例脑出血患者为研究对象,根据是否发生HAP分为病例组57例和对照组132例,采用多因素非条件Logistic回归分析分析急性脑出血患者ICU室罹患HAP相关危险因素.结果病例组患者在再出血率,病死率明显高于对照组,差异有显著的统计学意义 P<0.01,而BI评分明显低于对照组患者,差异有显著的统计学意义 P<0.01.多因素结果筛选出气管切开治疗；年龄≥60岁 OR=3.674；95%CI 0.757~14.745；吸烟 OR=76.775；95%CI 0.354~17.475；气管切开治疗 OR=26.464；95%CI 0.676~18.864；气管插管治疗 OR=25.346；95%CI 0.963~18.475；ICU住院时间 OR=5.772；95%CI 0.428~6.642；机械通气时间 OR=3.425；95%CI 0.208~6.277是急性脑出血患者ICU室罹患HAP的危险因素.结论急性脑出血患者ICU室罹患HAP预后较差,应尽量减少侵袭性操作的次数,尽可能地及早拔管,避免长时间在ICU住院和机械通气
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