17例儿童髂骨嗜酸性肉芽肿的治疗

摘要

分析儿童髂骨嗜酸性肉芽肿的临床特征及诊断治疗方法。方法选择郑州大学第三附属医院1998年1月～2012年1月儿童髂骨嗜酸性肉芽肿17例,施行病灶刮除同种异体骨植骨，局部注射甲泼尼龙琥珀酸钠治疗。结果全部病例随访1.5～7.4年，15例病灶消失未发现复发病灶,2例骶髂关节处残留病灶但无临床表现。结论儿童髂骨嗜酸性肉芽肿临床表现不典型，实验室及影像学检查特异性差，需要手术病理检查确诊。手术充分刮除病灶结合同种异体骨植骨可以防止髋臼塌陷，获得良好髋关节功能，局部注射甲泼尼龙琥珀酸钠治疗，可以防止复发。%To analyze the clinical features, diagnosis and treatment of esinophilic granuloma of bone(ECB) in children.Methods From January 1998 to January 2012, 17 cases of ECB in children were treated(male 11,female 6,mean age:6.7 years old)by curettage with bone allograft transplantation and direct injection of methylprednisolone sodium succinate, the diagnosis was confirmed by pathological examination. Results The time of follow-up ranged From 1.5 years to 7.4 years (3.7 years in average).15 patients cured with no recurrence and 2 patients demonstrated with lesions of the sacroiliac joint but had no clinical symptoms.Conclusion EGB of Ilium in children has atypical clinical symptoms and laboratory or imaging examination. Pathological examination would benecessary before surgery. Operation fully curett -age combined with allograft can prevent theacetabular collapse, obtain good hip function. Local injection of methylprednisolone sodium succinate can prevent recurrence.