血清钠与原发性上尿路结石的相关性研究

摘要

Objective To investigate the relationship between serum sodium and primary urinary stones.Method 258 cases with urinary calculus were chosen, according to the calculus components were divided into different group,Calcium oxalate stone in 180 cases, 39 cases, phosphate calculi uric acid calculi 35 cases, phosphate ash Shi Jieshi 4 cases, take after peripheral blood by automatic biochemistry analyzer check each serum electrolyte level, and mainly compared the difference of serum sodium, and compared with the test of 300 cases with normal comparison.Results The serum sodium level of stone group were obviously higher than that of normal control group, the difference had statistical significance between the two groups (P<0.05); Logistic regression analysis showed that, the male and female serum sodium level beta value were 0.12 (P<0.01) and 0.08 (P<0.05).Conclusion Serum electrolyte in primary urinary stones has different compared with normal control group, serum sodium level change may be an important factor causing urinary calculus.%目的：探讨血清钠浓度与原发性上尿路结石发生的相关性。方法选择中山市古镇医院258例原发性尿路结石患者，根据结石成分分为不同小组，草酸钙结石180例，磷酸盐结石39例，尿酸结石35例，磷酸灰石结石4例，取外周血后用自动生化仪检查各组血清电解质水平，比较血清钠的差异，并与同期检测的300例正常患者进行比较。结果各结石组血清钠水平明显高于正常对照组，2组比较差异具有统计学意义（P＜0.05）；Logistic回归分析显示，男性和女性血清钠水平β值分别为0.12（P＜0.01）和0.08（P＜0.05）。结论原发性尿路结石患者血清电解质与正常对照组存在差异，血清钠水平的变化可能是引起原发性尿路结石一个重要因素。