Objective To study the intervention effect of evidence-based nursing on efficacy and life quality in children with nephrotic syndrome. Methods 100 children with nephrotic syndrome treated in our hospital from June 2012 to January 2014 were selected and randomly divided into two groups. The control group (50 cases) was given routine nursing, the observation group (50 cases) was given evidence-based nursing intervention on the basis of control group. The clinical effect, hospitalization time and improvement of life quality in the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group (92.0%vs 68.0%), the hospitalization time was significantly shorter than that of the control group [(20.3±3.4) vs (27.8±4.9)] d, all the difference was statistical (P <0.05). The score of life quality in the two groups after intervention increased, and the score of the observation group was obviously higher than that of the control group, with statistical difference (P<0.05). Conclusions Evidence-based nursing intervention can significantly improve the efficacy of children with nephrotic syndrome, shorten the hospitalization time and improve their quality of life.%目的：研究循证护理在肾病综合征患儿治疗疗效及生活质量中的干预效果。方法以我院2012年6月至2014年1月收治的100例肾病综合征患儿为研究对象，随机将其分为两组各50例。对照组患儿给予常规护理，观察组患儿在对照组基础上行循证护理干预。比较两组患儿的临床疗效、住院时间及生活质量改善情况。结果观察组的总有效率显著高于对照组(92.0豫增泽68.0豫)，住院时间明显短于对照组[(20.3±3.4)增泽(27.8±4.9)]凿，差异均具有统计学意义(P<0.05)。干预后，两组生活质量评分均显著升高，且观察组评分明显高于对照组，差异具有统计学意义(P<0.05)。结论循证护理干预能明显提高晕杂患儿治疗效果，缩短住院时间，改善其生活质量。
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