不同高血压人群的降压目标值

摘要

Hypertension is a major independent risk factor for the development of coronary artery disease, stroke,and renal failure.The direct goal of antihypertensive therapy is to restore the blood pressure(BP)to the level of normal range,and the ultimate goal of hypertension is to reduce the risk of mortality and adverse events.Though some guidelines recommend more aggressive BP management in hypertensive patients, the target value of antihypertensive therapy is still uncertain because of lack of support in evidence-based medicine .The current review summarized BP reduction goals in different cohorts from the most recent guidelines.%高血压是冠心病、脑卒中和肾功能衰竭发展的一个主要独立危险因素。降压治疗的直接目的是达标，终极目的是降低患者的心血管事件风险。然而，降压治疗的目标值确定却缺乏足够的循证医学证据支持。因此，对于高血压患者，什么是合理的降压目标值，那些因素决定降压目标值成为临床实践中关注的焦点。本文将依据近年高血压指南对高血压不同人群的降压目标值做一综述。