3种不同扩弓方式对龈沟液AST、ALP水平影响的研究

摘要

Objective To discuss the relationship between three different expansion methods, including of RE, SE and ME on periodontal tissue remodeling.Methods 60 patients (aged 10.2 to12.5 years) who required opening of the palatal suture were divided randomly into RE group(20 cases) ,SE group(20 cases) ,ME group(20 cases).aspartate aminotransaminase(AST) and alkaline phatase(ALP) activities were determined by a full automatic biochemical analyzer during 6 observation periods-before activation,24 hours and 7days after activation,7 days、14 days and 28 days in retention.The results were expressed as the total of AST and ALP activities.Results AST activity was statistically significant different among three groups from 24 hours activation to 14 days in retention.ALP activity was statistically significant different among three groups from 24 hours activation to 28 days in retention.Conclusion These results indicate that GCF-AST and GCF-ALP levels may reflect periodontal tissue remodeling, and its suggest magnetic expansion could bring continuous and light force that is more favorable to periodontal tissue remodeling.The results will provide the favorable reference for orthodontic treatments.%目的 探讨快速机械扩弓(RE)、慢速机械扩弓(SE)及磁力扩弓(ME)方式与牙周组织改建的关系.方法 选择2007年7月至2009年7月海南医学院附属医院上颌扩弓患者60例,男女各30例,年龄10.2~12.5岁.将其分为快速机械扩弓(RE)组、慢速机械扩弓(SE)组及磁力扩弓(ME)组,每组20例.利用全自动化生化分析仪检测扩弓前、24 h、7 d,保持7、14、28 d龈沟液(GCF)中天冬氨酸转氨酶(AST)、碱性磷酸酶(ALP)活性的变化,比较3种扩弓方式对前、后GCF内AST和ALP水平的影响.结果 扩弓24 h～14 d,3种不同扩弓方式对GCF-AST水平影响不同(P＜0.05);扩弓24 h～28 d,3种不同扩弓方式对GCF-ALP水平影响不同(P＜0.05).结论 在口腔卫生良好时,GCF-AST、GCF-ALP水平一定程度上能反映牙周组织的改建,磁力产生持续不断的力,有利于牙周组织的改建.