Objective To improve the diagnosis and treatment of the primary duodenum tumor. Methods Twenty one patients with primary duodenal tumor treated operatively between 2004 and 2010 were analyzed retrospectively. Results Seventeen patients complained of epigastric pain,13 cases of nausea and vomiting,3 cases of jaundice,4 cases of abdominal mass,8 cases of discontin ued melena or tarry stool, 5 cases of blood stool, 3 cases of upper digestive tract obstruction. Four cases located in the duodenal bulb,14 cases in the descendant and 3 cases in the horizontal pars. 21 cases of primary duodenum tumor were operated and confirmed by pathology,one cases of the smooth muscle tumor,4 cases of stromal tumors, 5 cases of sarcoma and 11 cases of adenocar cinoma. Conclusion The first choice of the diagnosis in primary duodenum tumor is the upper gastrointestinal barium meal examination and biopsy of fiber duodenoscope. The operative type is choosed according to tumor site.%目的 提高对十二指肠肿瘤的诊治水平.方法 回顾性分析21例十二指肠肿瘤患者的诊断及治疗情况.结果 21例中腹痛17例,恶心、呕吐13例,黄疸3例,腹部包块4例,间断性黑便或柏油样便8例,血便5例,梗阻3例.发生于十二指肠球部4例,降部14例,水平部3例.病理细胞学检查1例为平滑肌瘤,4例为间质瘤,5例为肉瘤,11例为腺癌.结论 十二指肠肿瘤的诊断首选上消化道钡餐检查和纤维十二指肠镜活检,根据肿瘤部位选择手术方式.
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