Objective To investigate the local situation about mycoplasma infection as well as drug sensitive in renal and urogen ital disorder. Methods Used the mycoplasma diagnostic kits provided by the Quick Da Biology High Tech(shanghai)Co. LTD to take the mycoplasma culture and identification on 632 patients as well as the drug sensitive test. Results Mycoplasma positive case was 248 and the rate was 39.2％. This included Urea plasma urealyticum(UU)positive case 150 and the rate 23.7％, Mycoplasma hominis(MH)positive case 18 and the rate 2. 8％, UU merger of mycoplasma hominis(UU+ MH)positive case 80 and the rate 12.7％. The infection rate of people from 21 to 40 was apparently higher than that of other ages. The infection rate of UU female patient was 31.4 ％(127/404)and male patient was 10.1％(23/228). The susceptibility rates of the 13 kinds of antibiotics as follows :doxycycline 88.7 ％ ,josamycin 33.1 ％, ofloxacin 21.4 ％, roxithromycin 35.5 ％, sparfloxacin 21.4 ％, ciprofloxacin 3. 6 ％, az ithromycin 29.8％ ,clarithromycin 60.9％ ,minocycline 89. 1％ ,levofloxacin 24. 6％, norfloxacin 8.8％ ,spectinomycin 7.3％ ,linco mycin 2.8 ％. Conclusion Mycoplasma is the main pathogen of fei lin urethritis and it resists to a lot of antibiotics. Therefore myco plasma culture and drug sensitive tests should be set as a routine examination on renal and urogenital disorder.%目的 了解泌尿生殖道疾病中支原体感染的状况及药敏情况.方法 采用支原体诊断试剂盒,对632例泌尿生殖道感染患者进行支原体培养、鉴别以及药敏试验.结果 检出支原体阳性248例,检出率为39.2%,其中解脲支原体(UU)阳性150例,检出率为23.7%,人型支原体(MH)阳性18例,检出率为2.8%,解脲支原体合并人型支原体(UU+MH)阳性80例,检出率为12.7%;21～40岁年龄段患者的感染率明显高于其他年龄段;女性患者UU感染率为31.4%(127/404),男性患者UU感染率为10.1%(23/228).对13种抗菌药物的敏感率分别是:多西环素88.7%,交沙霉素33.1%,氧氟沙星21.4%,罗红霉素35.5%,司帕沙星21.4%,环丙沙星3.6%,阿奇霉素29.8%,克拉霉素60.9%,盐酸米诺环素89.1%,左氧氟沙星24.6%,诺氟沙星8.8%,大观霉素7.3%,林可霉素2.8%.结论 支原体为非淋菌性尿道炎的主要病原体,对多种抗生素产生耐药性,应将支原体培养和药敏试验当作泌尿生殖道疾病的常规项目进行检测.
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