Objective to study the use of Statins in patients with type 2 diabetes mellitus and blood lipid levels,and to analysis the use of statin drug in patients with diabetes mellitus. Methods 516 cases of over 40 years old type 2 diabetes outpatients with Hypoglycemic drugs treatment were randomly chosen and divided as diabetes combined with Coronary heart disease GroupCGl ,225 cases) and single diabetic Group(G2,291 cases) according to whether they had Coronary heart disease or not. Questionnaire method was applied to collect the general information of the patients, then we examined the level of glycosylated hemoglobin(HbAlc) , total cholesterol(TC) ,triglyceride(TG) ,high density lipoprotein cholesterol(HDL-C) , and low density lipoprotein cholesterol(LDL-C) to statistically describe and analyze the result of Statin use and qualification compliance rate in patients. Results 225 cases of G1 group matching the selected criteria with 93% taking statin drugs were chosen,229 cases from G2 group with 73% statin taking. In both Gl and G2 groups the qualification compliance rate of HbAlc and TC,TG was significantly larger than the cases that were not reaching the set of compliance(P<0. 05). Conclusion Compared with simple diabetes mellitus,the ration of statin drugs use in type 2 diabetes combined with coronary heart disease patients is higher, but the success rate of blood lipids of two groups are not ideal. HbAlc compliance can promotes TG compliance of two groups, it is of more significance to use Statins to reduce the LDL-C in early period.%目的 探讨2型糖尿病患者他汀类药物使用及血脂达标情况,以分析糖尿病患者他汀类药物使用现状.方法 随机选取四川省人民医院2011年6月至2012年3月年正在进行降糖药物治疗的门诊就诊的2型糖尿病患者516例,按是否患有冠心病分为合并冠心病组(G1组)225例和单纯糖尿病组(G2组)291例,采用问卷调查的方式收集患者一般情况,然后分别测定其糖化血红蛋白(HbA1c)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),对该类患者他汀类药物使用情况及达标情况进行统计描述和分析.结果 G1组和G2组患者服用他汀类药物的比例为93.33%、73.54%,G1组中HbA1c达标率及TG达标率明显大于HbA1c不达标组(P<0.05).G2组中HbA1c达标率TC、TG达标率明显大于HbA1c不达标组(P<0.05).结论 合并冠心病的2型糖尿病患者较单纯2型糖尿病患者他汀类药物使用率高,但两组血脂的达标率并不理想,HbA1c的达标有利于两组患者的TG的达标,早期应用他汀类药物降低LDL-C意义更大.
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