和胃抗逆丸治疗胃食管反流病的临床研究

摘要

Objective To explore the clinical effect of Heweijiangni granule on gastroesophageal reflux disease (GERD) .Methods 80 patients were randomly divided into two groups ,40 cases in each group .The treatment group were treated with Heweijiangni granule ,while the control group were treated with western routine therapies .The courses of treatment in two group were 8 weeks . Results The total symptom effective rate of treatment group was 92 .50% and the control group was 62 .50% ,differences between the two groups have statistical significance (P<0 .05) .But no significant difference was found between the two groups on esophage-al mucosa under gastroscopy(P>0 .05) .Conclusion Heweijiangni granule can improve the main symptoms such as heartburn ,pan-tothenic acid ,chest pain and regurgitation of GERD ,and the effect is very significant .%目的：探讨和胃抗逆丸治疗胃食管反流病（GERD）的临床疗效。方法将80例患者分为治疗组和对照组，每组40例。对照组给予常规西医治疗，治疗组给予和胃抗逆丸口服。8周为1个疗程。结果治疗组临床症状改善总有效率为92．50％，对照组为62．50％，两组差异有统计学意义（ P＜0．05）。两组胃镜下食管黏膜均有改善，但二者之间差异无统计学意义（P＞0．05）。结论和胃降逆丸能够很好地改善GERD患者烧心、泛酸、胸痛、反胃等主要症状，疗效显著。