低钠血症对慢性心力衰竭患者近期临床预后的影响

摘要

目的：分析低钠血症对心力衰竭患者临床预后的影响。方法回顾性分析2006年2月至2012年8月期间在解放军324医院诊疗的322例心衰患者，按照血清钠的浓度分为低钠血症组与正常血钠组，均为161例，比较分析两组患者的相关临床资料情况。结果低钠血症组BNP水平、住院天数、住院死亡率、再住院率分别较正常血钠组同一心功能患者明显升高（P＜0．05）；在低钠血症组，血钠浓度随着心功能的降低而降低（P＜0．05），随着血钠浓度的降低而BNP水平升高（P＜0．05），住院天数及住院死亡率随着心功能的降低而升高（P＜0．05）。结论心衰合并低钠血症患者具有心功能差、住院死亡率和再住院率高以及住院时间长的特点。%Objective To study the influence of hyponatremia on prognosis in hospitalized patients with chronic heart failure . Methods A total of 322 patients with chronic heart failure from Feb .2006 to Aug .2012 were retrospectively reviewed and random-ly divided into hyponatremia group(n=161) and normal serum sodium group(n=161) .The clinical data of the two groups were compared .Results There were significant difference between the two groups in the BNP levels ,length of stay ,hospital mortality and readmission rates(P<0 .05) .Serum sodium concentration in hyponatremia group was decreased with the decrease of cardiac function(P<0 .05) ,BNP levels was elevated with the decrease of blood sodium level (P<0 .05) ,days of hospitalization and hospital mortality were increased with the decrease of cardiac function (P< 0 .05) .Conclusion Patients with heart failure combined hy-ponatremia have poor cardiac function ,higher in-hospital mortality and readmission rates and longer hospital stay .