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肺微瘤型类癌10例临床特征分析及文献复习

     

摘要

Objective To retrospectively analyze the clinical characteristics ,pathological features and aetiology of pulmonary carcinoid tumourlets .Methods The clinical data of 10 patients with pulmonary carcinoid tumourlets in the West China Hospital of Sichuan University from April 1976 to October 2013 were collected for conducting the retrospective analysis and combining the lite‐raute review .Results Of the total 10 patients ,3 cases were male and 7 cases are female .9 cases were accompanied by bronchiecta‐sis ,1 case was complicated with lung adenocarcinoma .The clinical manifestations were lack of specificity ,which were dominated by repeated cough ,expectoration ,dyspnea and hemoptysis .The microscopic pathological examination suggested that there were differ‐ent degrees of inflammation reaction or fibrous tissue hyperplasia .All patients had no carcinoid syndrome ,lymph node and distant metastasis .10 cases received the surgical treatment .6 cases were pulmonary hypoplasia ,in which 1 case was carcinoid tumourlets complicating pulmonary sequestration .The postoperative follow up lasted for 5 - 80 months .8 cases had no recurrence and 2 cases were loss of follow up .Conclusion For the middle‐aged women patients with bronchiectasis and poor therapeutic effect ,complica‐ting carcinoid tumourlets should be vigilant ,active surgery combined with the pathologic examination is a suitable clinical decision .%目的:回顾性分析探讨肺微瘤型类癌的临床特点、病理特征及病因学。方法收集四川大学华西医院1976年4月至2013年10月确诊的10例肺微瘤型类癌患者的临床资料,并结合文献复习。结果10例微瘤型类癌患者男3例,女7例,9例伴支气管扩张,1例合并肺腺癌。其临床表现缺乏特异性,主要以反复咳嗽、咳痰、呼吸困难及咯血为主,镜下病理检查均提示有不同程度的炎性反应或纤维组织增生。所有患者均无类癌综合征、淋巴结转移及远处转移,行手术治疗,6例存在肺发育不良,其中1例为微瘤型类癌合并肺隔离症。术后随访5~80个月,8例无复发,其中2例失访。结论对于临床治疗效果欠佳的支气管扩张的中年女性患者,应警惕合并肺微瘤型类癌,积极手术并结合病理检查是适宜的临床决策。

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