高强度聚焦超声联合无水乙醇消融子宫肌瘤的研究

摘要

目的：探讨高强度聚焦超声（HIFU）联合无水乙醇注射（PEI）治疗子宫肌瘤的应用价值。方法178例的子宫肌瘤患者根据 MRI T2 WI信号分为 A类（低信号）82例、B类（等信号）61例及C类（高信号）35例，其中84例采用 HIFU联合 PEI介入治疗（HIFU＋PE治疗组），94例单纯采用 HIFU治疗（HIFU治疗组），分别记录相关治疗参数。结果 A类与 B类子宫肌瘤中，HIFU＋PEI治疗组子宫肌瘤在治疗时间、治疗能量上明显少于单纯 HIFU治疗组（P＜0．05）；C类子宫肌瘤中，HIFU＋PEI治疗组对子宫肌瘤的消融率明显高于单纯 HIFU治疗组（P＜0．05）。结论 HIFU术前行子宫肌瘤的 PEI治疗，可以明显提高HIFU治疗子宫肌瘤的效果。%Objective To discuss the applicative value of high intensity focus ultrasound(HIFU)combined with ultrasound-guided percutaneous ethanol injection(PEI)in treatment of hysteromyoma.Methods 178 patients with hysteromyoma were divided into three types:type A(low signal)82 cases,type B(signal)61 cases and type C(high signal)35 cases according to the MRI T2 WI signal,and 84 cases were treated with HIFU combined with interventional therapy of PEI(HIFU+PEI group),94 cases were trea-ted only with HIFU(HIFU group),treatment parameters were recorded respectively.Results Treatment time and therapy energy of HIFU combined with PEI in the treatment of hysteromyoma was less than that of the simple HIFU treatment group in uterine fi-broids of type A and type B(P<0.05).The uterine leiomyoma ablation rate of HIFU combined with PEI in the treatment of hyste-romyoma was higher than that of the simple HIFU treatment group in uterine fibroids of type C(P<0.05).Conclusion That PEI therapy is adopted to the treatment of hysteromyoma before HIFU opetation could obviously improve the treatment effect.