Synthesis, structure and biological activity of 3,7-dinitrodibenzobromonium salt

摘要

3,7-Dinitrodibenzobromonium bisulfate 3 was prepared directly by the reaction of4,4’ -dinitrobiphenyl with sodium bromide and potassium persulfate in the concentrated sulphuric acid. Metathetical reactions of 3 gave 3, T-dinitrodibenzobromonium chloride 4, bromide 5 and iodide 6, respectively. Crystal structure of 3a obtained by crystallization of 3 in formic acid showed that each molecule of 3a consists of two dibenzobromonium ions, two bisulfate anions and a formic acid. The dibenzobromonium ion is nearly coplanar. Compound 3 can dramatically increase mice’s immunofunction.