Objective To explore the feasibility of low-tube-voltage and low-concentration contrast agent applied to coronary computed tomography angiography (CTA) in the overweight patients. Methods Totally 83 overweight patients with suspected coronary heart disease who underwent coronary artery angiography were randomly assigned into two groups. Group A used 100 kVp and ioversol-320 mg/ml, and Group B received 120 kVp and iopamidol-370 mg/ml. Both the groups went through prospectively ECG-gated scanning. The two groups were compared on the image quality, radiation dose, iodine intake and coronary artery segments scores. Results The effective radiation dose and iodine intake in Group A were significantly lower than those in Group B (P<0.05). Group A had the coronary artery CT value and image noise lower significantly than Group B (P<0.05). No significant differences in signal to noise ratio, contrast to noise ratio and coronary artery segments scores were observed between the two groups (P>0.05). Conclusion For coronary artery CTA in the overweight patients, low-tube-voltage and low-concentration contrast agent still preserves the image quality, as well as significantly reduces the radiation dose and iodine intake.%目的:探讨采用低管电压和低浓度对比剂对超重患者行冠状动脉CT血管造影的可行性.方法:将83例因怀疑冠心病行冠状动脉CT血管造影的超重患者随机分为A、B 2组.A组采用100 kVp管电压,320 mg/ml碘佛醇;B组采用120 kVp管电压,370 mg/ml碘帕醇.2组均运用前瞻性心电门控扫描,对比分析2组图像质量、辐射剂量、碘摄入量及冠状动脉节段评分.结果:A组有效辐射剂量及碘摄入量明显少于B组(P<0.05);2组图像冠状动脉CT值、噪声比较差异均有统计学意义(P<0.05),A组低于B组;2组图像信噪比、对比噪声比及冠状动脉节段评分比较差异无统计学意义(P>0.05).结论:采用低管电压和低浓度对比剂对超重患者行冠状动脉CT血管造影不仅能保证图像质量,还可减少辐射剂量和碘摄入量.
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