志贺菌致病的分子机制

摘要

志贺菌是肠道内致病菌,无鞭毛不能运动,侵袭过程依靠T3SS分泌的效应分子.本文就志贺菌T3SS、参与侵袭过程的效应分子以及相应的致病机制作一综述.%Shigella spp. is an intestinal pathogenic bacteria without flagellum and non motile. Invasive process depends on effector molecules secreted by T3SS. In this paper, T3SS of Shigella spp. , effector molecules involved in the invasive process and the corresponding pathogenic mechanism are reviewed.