血管回声跟踪技术对2型糖尿病患者下肢血管弹性功能的检测

摘要

Objective To detect the elasticity of common femoral artery and popliteal artery in type 2 diabetes（T2DM）patients by using echo-tracking(ET) technique.Methods Thirty healthy subjects(control group) and sixty-eight T2DM patients were enrolled in this study.The longitudinal view of common femoral artery(CFA) and popliteal artery(PoA) were displayed in two-dimensional ultrasonic imaging.The stiffness parameter(β)，pressure-strain elasticity modulus(Eρ)，arterial compliance(AC)，argumentation index(AI) and one-point pulse wave velocity(PWVβ) of these arteries were automatically measured by ET technique.Results β，Eρ and PWVβ of CFA and PoA were significantly higher(P<0.05) and AC was significantly lower(P<0.05) in the T2DM group than those in the control group.Conclusions The elasticity of femoral and popliteal arteries both decreased in patients with T2DM.ET technology is a quick and non-invasive evaluating method for elasticity of lower limb arteries in T2DM patients.%目的 探讨血管回声跟踪技术(echo-racking,ET)对2型糖尿病患者下肢血管病变的诊断价值.方法 筛选30例正常人和68例2型糖尿病患者,在ET模式下采集股总动脉、腘动脉的二维超声图像,应用ET技术检测其动脉弹性指标:僵硬度指数(β),血管压力-应变弹性系数(Eρ),顺应性(AC),增大指数(AI),脉搏波传导速度(PWVβ).结果 糖尿病组股总动脉、腘动脉的β、Eρ、PWVβ较对照组显著增高(P<0.05),AC值显著降低(P<0.05),AI值与对照组相比差异无统计学意义(P>0.05).结论 糖尿病患者的股动脉存在动脉硬化,腘动脉作为肌性动脉也存在动脉硬化,且与弹性大动脉股动脉改变一致,有良好的相关性.ET技术为2型糖尿病患者下肢动脉的弹性检测提供了一种快速、无创的评价方法 .