1,5-二氮杂二环4.3.0-壬-5-烯与全氟烷基炔酸甲酯的Michael加成反应

摘要

Michael-type addition of 1,5-diazabicyclo [ 4.3.0 ] non-5-ene (DBN) with methyl 2-perfluoroalkynoates (2) occurred and subsequent intramolecular condensation of the adduct gave a tricyclic derivative(3). The structure of 3 was confirmed by elemental analysis, IR, MS and 1H NMR,13C NMR, 13C-1H cosy, 1H-1H cosy . The reaction mechanism was also proposed.%1,5-二氮杂二环[4.3.0]-壬-5-烯(DBN)与全氟烷基炔酸甲酯发生Michael加成反应,生成的中间体发生分子内缩合产生了三环化合物.其结构经元素分析,IR,MS和核磁共振氢谱、碳谱,二维核磁共振13C-1H cosy谱,二维核磁共振1H-1H cosy谱确认.对反应机理也进行了探讨.