强直性脊柱炎合并Andersson损害的研究进展

摘要

Andersson lesion is a destructive vertebral or disco-vertebral lesion that occurs in the late stage of the ankylosing spondylitis.According to the etiology,these lesions are usually classified into localized lesions and extensive lesions.The history of ankylosing spondylitis and characteristic imaging is the key to the diagnosis of Andersson lesion.Conservative treatment may be effective for localized lesions.However,surgical intervention is often required for the failure of conservative treatment and extensive lesions.Currently,the optimal procedure for this problem is spinal osteotomy through pseudarthrosis and debridement via posterior-only approach.%Andersson损害指发生于椎间盘-椎体界面的破坏性病损,是强直性脊柱炎晚期的一种少见并发症.依据病因分型,一般将Andersson损害分为局灶型病损和广泛型病损两大类型.强直性脊柱炎病史及独特的影像学征象是诊断Andersson损害的关键.对于局灶型病损,可先尝试保守治疗;而对于保守治疗无效的局灶型病损及广泛型病损,常需要手术干预,当前大多采取单纯后路经病灶截骨内固定矫形融合术.