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54例隐匿性甲状腺癌诊治的回顾性分析

     

摘要

目的:探讨隐匿性甲状腺癌的诊断方法及手术方式。方法:回顾性分析54例隐匿性甲状腺癌患者的临床病理资料,采用SPSS 13.0统计软件进行t检验、卡方检验及Kaplan-Meier生存曲线分析。结果:超声检查者54例,其中检出微小结节43例,CT检查者27例,其中14例发现甲状腺占位,9例有淋巴结转移;成功随访46例,其中甲状腺腺叶、峡部切除术者(腺叶、峡部切除组)32例,行甲状腺腺叶、峡部切除、改良颈淋巴结清除术(腺叶、峡部切除、淋巴结术组)者14例,死亡4例;腺叶、峡部切除组平均生存时间(84.0±29.5)个月,腺叶、峡部切除、淋巴结术组(75.6±36.8)个月(P=0.486)。结论:辅助检查是隐匿性甲状腺癌的必要诊断方法,手术为治疗隐匿性甲状腺癌的主要手段。%Objective To investigate the diagnosis and surgical therapy of occult cancer of the thyroid (OCT). Methods The clinicopathological data of 54 cases of OCT were retrospectively analyzed by SPSS13.0 statistical software through t testing, chi-square test and Kaplan-Meier method. Results All 54 patients were performed with ultrasonography and 43 cases were detected with mini nodules in the thyroid gland, 27 with CT scan and 14 cases with thyroid lesions; 11 patients were male and 43 female. Forty-six cases’ were fol-lowed-up, of them 32 patients underwent unilateral lobe with isthmus resection and 12 got modified radical neck dissection, four patients died respectively. The mean survival time of patients after unilateral lobe with isth-mus resection was(84.0±29.5)months, which was slightly higher than(75.6±36.8)months for those with modi-fied radical neck dissection, though there was insignificant difference in the survival rates between the two groups(χ2=0.485,P=0.486>0.05). Conclusion Accessary examinations are necessary to establish the diag-nosis for occult cancer of the thyroid (OCT), with surgical procedure as the major treatment method.

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