包皮环切与微波疗法联合治疗尖锐湿疣

摘要

Objective: To investigate the efficacy of combination of circumcision and microwave on genital warts in uncircumcised men.Methods: A randomized, prospective study of 109uncircumcised adult men with genital warts was conducted in a STD clinic in Zhanjiang, Guangdong. One group (n=54) received microwave therapy only, while the other group (n=55) was taken the combination of circumcision and microwave therapy. The recurrences were observed at the end of months 3, 6 and 12, and operative complications were also recorded.Results: There were no significant differences in the mean age and duration of the disease between two groups (P＞0.05). No serious operative complications were documented. The recurrence rate in circumcision plus microwave group was markedly lower than that in microwave group (12.7% vs 29.6%, P＜0.05),while the differences in early and late recurrences between two groups showed no statistical significance (P＞0.05).Conclusion: Circumcision can be safely performed under local anesthesia in an outpatient setting. Combination of circumcision and microwave can produce excellent effect as well as less tissue damage,therefore, it may be ideal for uncircumcised patients with extensive condylomas.%目的 对未接受过包皮环切手术的尖锐湿疣患者,给予微波与包皮环切联合治疗,并观察其疗效.方法 随机抽取某性病门诊109名未做过包皮环切手术的成年尖锐湿疣患者,将其分为两组进行前瞻性研究.一组(54人)接受单纯微波疗法,另一组(55人)接受微波与包皮环切联合疗法.我们观察到在第3,6和12个月后有复发出现,并记录术后合并症的发生情况.结果 两组间的平均年龄和病程无显著性差异(P＞0.0 5).未发现严重的术后并发症.微波与包皮环切联合治疗组的复发率明显低于单纯微波治疗组(12.7％和29.6％,P＜0.05),而两组间早期与后期的复发率差异无统计学意义(P＞0.05).结论 包皮环切术是一种安全的门诊手术,在局麻状态下即可进行.微波与包皮环切联合疗法的疗效显著,组织损伤小,是未接受过包皮环切手术的尖锐湿疣患者可选择的理想疗法.