Objective:To evaluate the effect of stellate ganglion block combined with dexmedetomidine in the treatment of migraine. Methods:Forty-six cases of migraine were randomly divided into two groups equally. Both groups received stellate ganglion block therapy. Observation group was given 0. 5μg/mL dexmedetomidine(0. 1mg/kg) ,and control group was simply supplemented with equivalent normal saline. The onset and duration time of nerve block and adverse effects were recorded. The analgesic effect was assessed by visual analogue scale(VAS) score at the 1st, 2nd,4th and 8th week after treatment. Results:The duration of block was obviously longer,and VAS scores at 2nd, 4th and 8th week after treatment were less in observation group than in control group(P<0. 05). There was no significant difference in perioperative adverse reactions and block onset time between two groups. Conclusion: Stellate ganglion block assisted with dexmedetomidine in the treatment of migraine was more effective than simple stellate ganglion block,and has no significant adverse effects.%目的:评价星状神经节阻滞辅助右美托咪啶治疗偏头痛的效果.方法:偏头痛患者46例,随机分为2组各23例.2组均行星状神经节阻滞治疗,观察组加用浓度为0.5μg/ml右美托咪啶0.1mg/kg辅助治疗,对照组辅以等量生理盐水.记录阻滞起效时间、维持时间和术中不良反应.于治疗后1、2、4和8周分别采用视觉模拟评分(VAS)评价疼痛程度.结果:观察组较对照组阻滞维持时间明显延长(P＜0.05)；治疗后2、4和8周VAS评分较对照组明显下降(P＜0.05)；2组患者围手术期不良反应发生率及阻滞起效时间比较差异无统计学意义.结论:与单纯星状神经节阻滞相比,星状神经节阻滞辅助右美托咪啶辅助治疗偏头痛更有效,且无明显不良反应.
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