脊髓损伤后神经源性逼尿肌过度活动的神经调节疗法

摘要

Neurogenic detrusor overactivity (NDO) often occurs after spinal cord injury, which often causes urinary tract infection, vesi-coureteral reflux, or even renal failure, and seriously impacts on the patient's quality of life. This paper reviewed the mechanism, the com-mon treatment methods, and neuromodulation theray of NDO after spinal cord injury, and elaborated percutaneous posterior tibial nerve stimulation, pudendal nerve regulation and the sacral neuromodulation respectively.%脊髓损伤后，很多患者出现逼尿肌过度活动，常常引起泌尿道感染、膀胱输尿管返流，甚至肾衰竭，严重影响患者的生活质量。本文结合脊髓损伤后膀胱逼尿肌过度活动的发生机制、一般治疗方法及神经调节疗法进行综述，并分别对经皮胫后神经调节、阴部神经调节和骶神经调节展开阐述。