Objective To compare the difference between the ACE-R scale and MoCA scale in assessing MCI patients . Methods 182 elders were enrolled in this research .According to the level of cognitive ,patients were divided into three groups in-cluding normal control group (NC) ,MCI group and AD group ,each with 70 NC individuals ,52 MCI patients and 60 AD patients , respectively .The neuropsychological tests in different groups such as the ACE-R ,MoCA were completed .Receiver operating char-acteristic(ROC)curve was adopted for comparing differences .Results Compared with group NC ,group MCI showed statistical difference on ACE-R and MoCA scale scores(P<0.001) ,the scores of memory component were mostly decreased .ROC results showed that the two scales both had high sensitivity ,the total time to assess ACE-R scale was significantly more than MoCA scale .Conclusion Both scales can evaluate MCI ,MoCA had advantages of less time consuming ,ACE-R assessment can assess MMSE score and each factor at the same time ,and ACE-R has a higher sensitivity in memory component score .Therefore ,in the clinical work ,MoCA assessment has an advantage in early screening ;The ACE-R scale can get more detailed information ,facilitate to follow-up in the future .%目的 在轻度认知功能障碍(MCI)人群中比较Addenbrooke改良认知评估量表(ACE-R)和蒙特利尔认知评估量表(MoCA)认知能力评价的差异.方法 共入组MCI患者52例,AD患者60例,正常的退休老年人70例为对照组.全部完成MoCA、ACE-R量表,比较各组量表评分及耗时,并用ROC曲线分析两个量表的敏感性.结果 MCI组的MoCA评分和ACE-R总分、注意和定向、记忆、语视空间评分显著低于正常对照组(P<0.001),其中ACE-R记忆分项值下降最快.ROC曲线结果提示两者均有很高的敏感度,但ACE-R量表评估耗时显著多于MoCA量表评估.结论 两项量表均能很好的评估MCI,MoCA评估具有耗时少的优势,ACE-R评估可同时获得MMSE得分及各项因子分,且ACE-R记忆分项得分敏感度最高.因此,在时间相对紧张的临床工作中,MoCA评估在初筛方面有优势;而ACE-R可获得更详尽的信息,便于日后随访.
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