Nanofat移植的进展

摘要

1893年德国外科医生Gustav Neuber首次报道了自体脂肪移植术,现自体脂肪移植的技术手段、移植理念和应用范围已经有了巨大的变化和进步,近年来,随着对脂肪来源干细胞研究的深入及应用的开展,自体脂肪的治疗范围进一步扩大,从最初用于软组织填充治疗,逐步扩展到了整形外科、修复重建外科和美容外科等领域,如瘢痕治疗、皮肤肌腱粘连治疗、雷诺综合征治疗、丰乳、面部年轻化及身体塑形等.起源于自体脂肪移植的Nanofat移植技术,尽管就此技术本身来说并不是真正意义上的纳米技术,但由于其在局部皮肤年轻化方面疗效显著,近年来成为了整形外科领域中的研究热点之一.%Since the autologous fat transplantation was reported by a German surgeon,Gustav Neuber,in 1893,the technical method of autologous fat transplantation,the transplantation concepts and application range have undergone tremendous changes and progress.In recent years,with the advanced research on adipose derived stem cells (ADSCs),the application field of autologous fat has been widespread.From initially used for soft tissue filling,it gradually expanded to orthopedic surgery,reconstructive surgery and cosmetic surgery,such as treatment of scar,skin and tendon adhesion,Renault syndrome,breast enhancement,facial rejuvenation and body shaping.The Nanofat transplantation technology originated from autologous fat transplantation,and it is not an exact nanotechnology for the technology itself.However,due to its remarkable effect on local skin rejuvenation,the Nanofat transplantation has become one of the hot issues in orthopedics in recent years.