肥胖人群腹部脂肪含量与阻塞性睡眠呼吸暂停综合征的关系

摘要

Objective To explore the relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people.Methods From July 2009 to July 2010,50 patients with BMI ＞ 25 were prospectively selected for study from the patients who complained of snoring in the Respiratory department.The patients were divided into OSAHS group and non-OSAHS group according to the result of sleep apnea monitoring.All the patients also received full abdominal CT and the whole abdominal fat volume was measured by 3-D CT reconstruction system.SPSS 13.0 was used for statistical analysis.Results The whole abdominal fat volume in the two groups was analyzed by T-test,which was significantly different between the two groups(P ＜ 0.01).It showed that there was a statistical relationship between OSAHS and abdominal fat in obesity people.Conclusions In obesity people,OSAHS has a close relationship with abdominal fat volume.The abdominal fat volume is markedly higher in OSAHS patients than that in non-OSAHS people.%目的 探讨在国人体重过重者(BMI＞ 25)中,阻塞型睡眠呼吸暂停综合征(OSAHS)患者与非OSAHS患者腹部脂肪含量的区别,及腹部脂肪对OSAHS的影响.方法 对北京朝阳医院呼吸内科2009年7月至2010年7月收治的主诉打鼾患者中BMI＞ 25的病例进行前瞻性研究,共25例,为OSAHS组(病例组),另征集无打鼾主诉,BMI＞ 25的志愿者30例,为非OSAHS组(对照组).对2组均进行睡眠呼吸监测诊断及全腹部CT影像学检查,CT三维重建系统测量全腹部脂肪体积.数据采用SPSS 13.0统计软件处理.结果 病例组与对照组腹部脂肪含量经采用t检验进行组间比较,病例组的腹部脂肪含量明显高于对照组(P＜0.01),OSAHS与腹部脂肪含量的关系有统计学意义.结论 肥胖人群中,OSAHS与腹部脂肪含量的关系密切,体重过重者,OSAHS患者的腹部脂肪含量明显高于对照组.