广西南宁地区健康人群骨密度十年前后比较

摘要

Objective To compare the change of bone mineral density and the prevalence of osteoporosis between 10 years ago and the present among the people who participate in health examination in Nanning, Guangxi.Methods This cross-sectional survey enrolled 2524 20-80-year-old healthy adults who participated in health examination from January 2011 to June 2012 in People’ s Hospital of Guangxi Autonomous, and the data were compared with those of 1058 cases from the same hospital 10 years ago.Bone mass density ( BMD) was detected using the same dual-energy X-ray absorptiometry ( DEXA) .Results The age of peak bone mass in males and females was 30-39 years old, which was the same as 10 years ago.In the 30-39 years old group, the BMD values of the femoral neck, Ward’ s triangle, Troch area, and the lumbar vertebrae ( L2、L3、L4) were not significantly different both in males and females over the past 10 years.The incidence of osteoporosis in total elderly population, elderly males, and elderly females ( 16.56% vs 17.78%, 12.30% vs 18.28%, 19.21% vs 17.31%, respectively, P >0.05 ) was not statistically different in 60-80 age group of between 10 years ago and the present.Conclusion Although the environment factors such as life style and self-care consciousness change a lot over the past 10 years, favorable factors and unfavorable factors that can influence bone metabolism coexist.As a result, there is no significant difference in the peak bone mass and the prevalence of osteoporosis in elderly adults .%目的：比较广西南宁地区十年前后健康体检人群骨密度变化及骨质疏松患病率。方法横断面调查2011年1月－2012年6月在广西壮族自治区人民医院进行健康体检的20－80岁人群2524例的骨密度情况，并与十年前1058例横断面调查比较，骨密度检测采用同一台双能X线骨密度仪（ DEXA）。结果男性和女性骨峰值年龄均为30－39岁，与十年前的结果一致。在30－39岁人群组中，十年前后男、女在股骨颈、ward三角、大转子、腰椎（ L2、L3、L4）骨密度值比较无统计学意义；60－80岁的老年总人群、老年男性和老年女性十年前后骨质疏松患病率（16．56％对17．78％，12．30％对18．28％，19．21％对17．31％，均P＞0．05）差异均无统计学意义。结论虽然十年前后环境因素包括生活方式和人们保健意识等发生较大变化，但影响骨代谢的有利因素和不利因素共存，因此，导致男女骨峰值水平和老年骨质疏松患病率无显著性差异。