通过1例Paget’s骨病的治疗分析，探讨其病因、诊断及治疗。 Paget’s骨病临床表现为慢性骨痛、骨畸形，血碱性磷酸酶持续增高， X线片及骨扫描有特异性改变。 Paget’s骨病在我国罕见，排除相关疾病时应想到该病的可能，治疗以双膦酸盐为主，首选唑来膦酸。%Paget’s disease of bone is a rare malady in China.Here we reported a case of 77-year-old female pa-tient suffered from intermittent bone pain complied with dysacousis.Laboratory tests showed sustained increased serum al-kaline phosphatase.The typical radiographic changes were found on her skull and lumbar spine.The diagnosis of PDB was made based on these manifestation.After the treatment with pamidronate, the serum alkaline phosphatase decreased and the bone pain was relieived gradually.The related literature was reviewed.
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