以3-芳基-5-巯基-1,2,4-三唑为原料,在酸性条件下与乙酰丙酮和乙酰乙酸乙酯一步成环,制各得到12种新的2-芳基-5-取代-6-甲基噻唑并[3,2-b](1,2,4)-三唑类衍生物.所有化合物结构经IR,1H NMR,13C NMR和MS及元素分析确证.%Twelve novel compounds, 5-(substituted phenyl)-2-substituent-3-methylthiazolo[3,2-b](1,2,4)-triazole derivatives, were synthesized by a one-pot reaction of 3-(substituted phenyl)-4,5-dihydro-1,2,4-triazole-5-thiones with acetylacetone or acetylaeetie ester in the presence of acid. The structures of the compounds were confirmed by IR, 1H NMR, 13C NMR, MS techniques and elemental analysis.
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