亲属脾移植治疗血友病甲长期存活的追踪报道

摘要

本文对我所1989年以来施行的4例亲属脾移植治疗血友病甲的长期存活情况作了追踪报道.4例中3例为母亲供脾,1例为父亲供脾,均获得了满意的疗效.1年内Ⅷ:C水平明显上升,1年后仍能显著改善患者的临床出血症状,后3例患者至今移植脾保持有功能,最长者达4年,创下了脾移植最佳世界纪录.%This paper reports four cases of living related splenic transplantation for the treatment of hemophilia A,performed since 1989.Three cases were mother to son,and one father to son.The good results have been achieved in all four cases.After the transplants.the Ⅷ:C levels rose significantly for more than one year.The clinical phenomena of bleeding reduced markedly afterward.Up to now,three grafts still functionally survived,and the longest one was over four years.These are the best record in the world.