Objective: To determine the effects of moderately intense aerobic exercise on intraocular pressure in young healthy adults. Methods: Twenty-eight volunteers performed moderately intense aerobic exercise for 30 minutes on a treadmill in this prospective study. Measurements of intraocular pressure (IOP), blood pressure and ocular perfusion pressure (OPP) were taken before and after exercise for 10, 20 and 30 minutes and after rest for 10 and 30 minutes. IOP was measured by iCare tonometry. Blood pressure was measured by an electronic sphygmomanometer. OPP was calculated using the formula, OPP=2/3 MAP (mean arterial pressure)-IOP. A repeated measures analysis was used to compare IOP, SBP, DBP and OPP. Results: Finally, 27 cases 27 eyes were included. ①There was a statistically significant difference (F=75.0, P<0.001) in IOP at baseline, and after moderately intense aerobic exercise for 10, 20 and 30 minutes andafter rest for 10 and 30 minutes. IOP at 10, 20 and 30 minutes of exercise was significantly lower than that at baseline (all P<0.001). ②There were statistically significant differences (F=31.7, P<0.001; F=19.7, P<0.001) in the SBP and DBP at baseline, and after moderately intense aerobic exercise for 10, 20 and 30 minutes and after rest for 10 and 30 minutes. SBP and DBP at 10, 20 and 30 minutes of exercise were significantly higher than that at baseline (all P<0.001). ③There was a statistically significant difference (F=56.9, P<0.001) in the OPP at baseline, and after moderately intense aerobic exercise for 10, 20 and 30 minutes and after rest for 10 and 30 minutes. OPP at 10, 20 and 30 minutes of exercise was significantly higher than that at baseline (all P<0.001). ④There were no statistically significant differences in IOP, SBP, DBP or OPP at baseline and after rest for 10 and 30 minutes. Conclusion: There is a significant decrease in IOP and significant increase in SBP, DBP and OPP following moderately intense aerobic exercise. After 10 minutes of rest, IOP, SBP, DBP and OPP return to baseline.%目的:探讨中等强度有氧运动对健康青年人眼压的影响.方法:前瞻性研究.选取中南大学爱尔眼科学院2016级、2017级硕士研究生28例(28眼),其中男14例,女14例,所有受试者均在同一跑步机进行中等强度运动,速度为7～9 km/h.采用iCare-pro眼压计测量右眼眼压,臂式血压计测量血压,根据公式"眼灌注压=2/3平均动脉压-眼压"计算.分别收集运动前,运动期10、20、30 min,休息10、30 min共6个时间点的数据.采用重复测量方差分析对数据进行分析.结果:最终纳入27例(27眼):①不同时间点眼压总体差异有统计学意义(F=75.0,P<0.001),运动期10、20、30 min较运动前眼压均降低,差异均有统计学意义(P<0.001).②不同时间点收缩压、舒张压总体差异均有统计学意义(F=31.7,P<0.001;F=19.7,P<0.001),运动期10、20、30 min收缩压、舒张压较运动前均升高,差异均有统计学意义(P<0.001).③不同时间点眼灌注压总体差异有统计学意义(F=56.9,P<0.001),运动期10、20、30 min眼灌注压较运动前均升高,差异均有统计学意义(P<0.001).④运动后休息10 min,眼压、收缩压、舒张压、眼灌注压与运动前差异均无统计学意义.结论:中等强度有氧运动使健康青年人眼压降低,血压及眼灌注压升高,运动后休息10 min,眼压、血压、眼灌注压均恢复至运动前水平并趋于稳定.
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