子宫颈上皮内瘤变治疗的新挑战

摘要

由于腔内后装技术和近距离放疗剂量学的进步，腔内后装放疗可以得到与宫颈锥切类似的剂量分布，用于临床治疗子宫颈上皮内瘤变，称之为后装锥切。后装锥切通过调节放射源的运动和权重，保障了卵巢受量低，子宫内膜不受破坏，阴道不狭窄，保证了患者治疗后的生活质量，并克服了宫颈锥切、子宫切除的缺点，如麻醉、出血、过度治疗、治疗不足、卵巢早衰及术后并发症的缺点而受到临床医师的关注。%Due to the progress of intracavitary afterloading technology and dosage of brachytherapy, a similar dose distribution as that of cervical conization can be achieved and can be applied to the treatment of cervical intraepithelial neoplasia ( CIN ) , it is called “afterloading conization”. Being adjusted the radioactive source movement and weight, low exposure doses to the ovary, endometrium and vagina can be assured. So a high quality of life after treatment could be maintained and overcomes the shortcomings of cervical conization and hysterectomy, such as anesthesia, bleeding, over or insufficient treatment, early ovarian ageing and operative complications.